← DISCOVERY / CANNABINOID

Cannabidiol

CBD

Major non-intoxicating cannabinoid of Cannabis sativa. Acts at multiple targets — CB1 negative allosteric modulator, CB2 partial agonist, 5-HT1A, TRPV1, GPR55 — producing anxiolytic, anticonvulsant, and anti-inflammatory effects without the classical cannabis 'high'.

sedative
Chemical structure of Cannabidiol
Structure · Wikimedia contributor See Wikimedia
THREE-DIMENSIONAL STRUCTURE

The molecule, in space.

Atoms positioned in their lowest-energy 3D geometry, sourced from PubChem. Drag to rotate · scroll to zoom · switch between stick, sphere, and line representations to feel the shape from different angles.

3D structure · PubChem CID 644019 · drag to rotate · scroll to zoom
SMILES NOTATION
CCCCCC1=CC(=C(C(=C1)O)C2C=C(CCC2C(=C)C)C)O
PubChem CID 644019 →
RECEPTOR PROFILE

The pharmacological targets through which this compound exerts its effects.

CB1 negative allosteric modulatorCB2 partial agonist5-HT1A agonistTRPV1 agonist
REFERENCES
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RELATED MOLECULES

Other cannabinoids

All compounds →
Chemical structure of THC
Cannabinoid
1–3 hours (inhaled) / 4–8 hours (oral)
THC
Δ9-Tetrahydrocannabinol
psychedelicsedative

The principal psychoactive cannabinoid in Cannabis sativa. Partial agonist at the CB1 receptor of the endocannabinoid system, with widespread effects on perception, appetite, time-sense, memory, and pain modulation.

Cannabis sativa
Examine →