THC

Δ9-Tetrahydrocannabinol · Delta-9-THC

The principal psychoactive cannabinoid in Cannabis sativa. Partial agonist at the CB1 receptor of the endocannabinoid system, with widespread effects on perception, appetite, time-sense, memory, and pain modulation.

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Structure · Wikimedia contributor See Wikimedia

THREE-DIMENSIONAL STRUCTURE

The molecule, in space.

Atoms positioned in their lowest-energy 3D geometry, sourced from PubChem. Drag to rotate · scroll to zoom · switch between stick, sphere, and line representations to feel the shape from different angles.

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3D structure · PubChem CID 16078 · drag to rotate · scroll to zoom

SMILES NOTATION

CCCCCC1=CC(=C2C3CC(=CCC3C(OC2=C1)(C)C)C)O

PubChem CID 16078 →

RECEPTOR PROFILE

The pharmacological targets through which this compound exerts its effects.

CB1 partial agonistCB2 partial agonist

NATURAL SOURCES

Living organisms in which this compound is naturally found.

Annual flowering plant whose resinous female inflorescences produce dozens of cannabinoids — chiefly Δ9-THC and CBD. One of humanity's oldest cultivated plants, with archaeological evidence of use stretching back at least five thousand years.

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REFERENCES

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RELATED MOLECULES

Other cannabinoids

Major non-intoxicating cannabinoid of Cannabis sativa. Acts at multiple targets — CB1 negative allosteric modulator, CB2 partial agonist, 5-HT1A, TRPV1, GPR55 — producing anxiolytic, anticonvulsant, and anti-inflammatory effects without the classical cannabis 'high'.

Cannabis sativa

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