Active metabolite of ibogaine, formed by demethylation in the liver. Substantially longer half-life than the parent compound and a notable serotonin reuptake inhibitor — widely considered responsible for much of ibogaine's anti-addictive afterglow.
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CCC1CC2CC3(C1N(C2)CCC4=C3NC5=CC(=CC=C45)O) The pharmacological targets through which this compound exerts its effects.
Complex pharmacology including NMDA antagonism, serotonin reuptake inhibition, and sigma receptor activity. Famous for interrupting opioid addiction and producing long, dream-like visionary states.
Iboga-type alkaloid found in Voacanga africana and Tabernanthe iboga and used industrially as the precursor for ibogaine synthesis. Pharmacologically similar to ibogaine but somewhat weaker.